TURIN - Inter sit on top of the table after 270 minutes of Serie A football after a 3-1 victory over Torino at the Stadio Olimpico.
Brazilians Mancini and Maicon stunned the Granata with goals in the space of two first-half minutes, before Zlatan Ibrahimovic wrapped up the points just after the restart.
Torino reduced the deficit through Elvis Abbruscato with 14 minutes remaining and kept Julio Cesar busy in the final stages.
Cristian Chivu made his return to the starting lineup as Mourinho fielded a 4-3-3 with an attacking trio of Ibrahimovic, Mancini and Adriano - back in the starting XI for the first time since last October's match against Reggina.
Toro made a bright start and all their front men had chances in the early stages, with Amoruso and Rosina firing wide before Bianchi rose to head behind.
Inter broke the deadlock on 24 minutes when Adriano played in the unmarked Mancini, whose cross-shot went in off Pisano.
Maicon doubled the lead inside two minutes, finding the top-left corner with a sweetly struck right-foot shot after collecting Vieira's pass.
Ibrahimovic made it 3-0 six minutes after the break, slotting past Sereni from ten yards after taking Mancini's pass into the area.
The Nerazzurri continued to pressurise Torino with some flowing counter-attacks but De Biasi's men were given a lifeline when Abbruscato slid home from close range after meeting Saumel's left-wing cross.
Rallied by their goal, the Granata came looking for more and Bianchi forced Julio Cesar into a reflex block with a flicked header before Abbruscato headed against the bar.
Torino 1-3 Inter (HT: 0-2)
Scorers: Mancini 24, Maicon 26, Ibrahimovic 51, Abbruscato 76.
Torino: 1 Sereni; Diana, 22 Di Loreto, 50 Pratali, 3 Pisano; 27 P.Zanetti (6 Ogbonna 66), 5 Corini (8 Barone 46), 24 Saumel; 10 Rosina (9 Abbruscato 29), 11 Amoruso; 90 Bianchi.
Subs not used: 99 Calderoni, 7 Ventola, 32 Colombo, 33 Rubin.
Coach: Gianni De Biasi.
Inter: 12 Julio Cesar; 13 Maicon, 16 Burdisso, 23 Materazzi, 26 Chivu; 14 Vieira, 19 Cambiasso, 4 Zanetti; 10 Adriano (45 Balotelli 67), 8 Ibrahimovic (9 Cruz 88), 33 Mancini (77 Quaresma 64).
Subs not used: 1 Toldo, 2 Cordoba, 18 Crespo, 24 Rivas.
Coach: José Mourinho.
Referee: Stefano Farina (Novi Ligure).
Booked: P.Zanetti 18, Pisano 28, Balotelli 74, Pratali 78.