MILAN - Defending champions Inter are joined on top of the Serie A table by Udinese and Napoli after being held to a goalless draw by Genoa in Week 8.
There was no way through at the Stadio Giuseppe Meazza as Gasperini's men ended the Nerazzurri's sixty-match scoring run in home league games.
Mourinho's men were quickest out of the blocks and could have taken a 2nd-minute lead through Ibrahimovic after a cross from Quaresma.
Genoa captain Marco Rossi then missed a sitter from two yards out after a cross from Diego Milito, who continued to apply the pressure when he had a header saved in the 22 minute.
Inter rallied and Ibrahimovic sent a fine shot just over before Quaresma narrowly missed the top right corner with a curling shot.
Unfazed, the Rossoblu hit back and Ivan Juric blasted wide his follow-up after Julio Cesar parried Milito's shot. Seconds later, Mesto saw his long-range effort bounce back off the bar.
Mourinho shuffled his pack at the break, introducing pacy strikers Balotelli and Obinna for Adriano and Quaresma, and the Nigerian almost had an instant impact when he fired wide after sidestepping Criscito.
The Inter boss was forced to make his third change just ten minutes in, bringing on Julio Cruz after Muntari was stretchered off injured.
Genoa survived a let-off when Marco Rossi unwittingly headed Maicon's cross on to the bar, and Inter's task looked to have been simplified when Juric was dismissed for a second booking in the 60th minute.
The Nerazzurri peppered the Genoa area with shots in their frantic search for a goal. Balotelli was twice thwarted by Rubinho, with Chivu and Obinna firing wide and Julio Cruz going close with a cross-shot.
Against the run of play, the visitors almost snatched a winner deep in injury time when Julio Cesar made a good save from Motta's free kick.
Inter suffered a second midfield injury blow in time added on when Stankovic pulled a muscle while making a defensive clearance.
Inter 0-0 Genoa
Inter: 12 Julio Cesar; 13 Maicon, 2 Cordoba, 16 Burdisso, 26 Chivu; 4 Zanetti, 5 Stankovic, 20 Muntari (9 Cruz 55); 77 Quaresma (21 Obinna 46), 8 Ibrahimovic, 10 Adriano (45 Balotelli 46).
Subs not used: 1 Toldo, 6 Maxwell, 23 Materazzi, 33 Mancini.
Coach: José Mourinho.
Genoa: 83 Rubinho; 15 Papastathopoulos, 25 Biava, 13 Ferrari; 20 Mesto, 88 Motta, 28 Juric, 4 Criscito; 7 Rossi (26 Bocchetti 84), 22 Milito (17 Jankovic 78), 14 Sculli (68 Vanden Borre 64).
Subs not used: 73 Scarpi, 3 Potenza, 8 Roman, 29 Brivio.
Coach: Gian Piero Gasperini.
Referee: Daniele Orsato (Schio).
Booked: Muntari 12, Criscito 25, Ferrari 87, Mesto 50, Juric 51, 60, Burdisso 69.
Sent off: Juric 60.