MILAN - Inter beat Roma 3-1 at the Meazza to seal a 4-2 aggregate victory and keep the Coppa Italia in Milan for another year.
Esteban Cambiasso and Julio Cruz scored first-half goals to put Inter in total command, with Obafemi Martins adding the third after the restart before Nonda's late consolation for the Giallorossi.
Cambiasso fired Inter ahead after six minutes with a cracking 20-yard volley from Javier Zanetti's cross.
Roma custodian Doni kept out efforts from Adriano, and Cruz shot narrowly wide before the Argentine striker doubled in added time at the end of the first half.
Meeting a through ball from Stankovic, Cruz rounded Doni and slotted into an open net for his twentieth of the season.
With Roma needing to score twice, Luciano Spalletti made a switch early in the second half. The whole stadium applauded as Francesco Totti replaced Okaka Chuka to make his return to competitive football after an 81-day absence through injury.
The talismanic Totti went close to scoring midway through the half, firing inches wide from a Kharja cut-back.
But Inter dampened any hopes of a Roma comeback in the 77th minute when Obafemi Martins received short from Cruz in the area and rammed into an open goal with Doni stranded.
Nonda reduced the arrears three minutes later with a header from a Totti free kick, but Inter defended their two-goal lead in the final minutes to give the club its second consecutive domestic cup triumph.
Inter coach Mancini enters the record books as the first coach to win three Italian Cups in a row, and equals Sven Goran Eriksson's record of four Coppa successes.
INTER 3-1 ROMA (HT: 2-0, AGG: 4-2)
Scorers: Cambiasso 6, Cruz 45+2, Martins 77, Nonda 80
INTER: 12 Julio Cesar; 4 J.Zanetti, 23 Materazzi, 25 Samuel, 16 Favalli; 7 Figo (18 Kily Gonzalez 81), 8 Pizarro, 19 Cambiasso, 5 Stankovic (21 Solari 58); 10 Adriano (30 Martins 67), 9 Cruz
Subs not used: 1 Toldo, 3 Burdisso, 14 Veron, 33 Wome
Coach: Roberto Mancini
ROMA: 32 Doni; 2 Panucci, 13 Chivu (4 Kuffour 12), 3 Bovo, 25 Cufrè; 14 Kharja (40 Nonda 76), 15 Dacourt; 28 Rosi, 17 Tommasi, 30 A.Mancini; 35 Okaka Chuka (10 Totti 54)
Subs not used: 1 Curci, 7 Alvarez, 16 De Rossi, 29 Greco
Coach: Luciano Spalletti
Referee: Domenico Messina (Bergamo refereeing section)
Booked: Kharja 36, Pizarro 43, Materazzi 80, Rosi 83, Bovo 84